SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27e3e6230fc01ec6452d92fdad8f4494c5eb63846b63130df0757ef7f66f4a5f' 
  AND token = 'BxZIBoDgMbpw7p/a3daOnkT8sXs2dWKDMFf51swZ8Zo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}