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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5debe64a6ebde957647c8481fdec9a2356bc6c513f595651de47da8b6d9f01ae' 
  AND token = 'oUB4H2S/ywVU8vsr1BPPUQyMi3m94i6VtvmlW8zSDZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}