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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39ec660d4df5938c59c8e096b249ba7f1daa6a6bf3f9caa41c98d2a5f44dca55' 
  AND token = 'wmWnmnu2E00Zds/8NSISgWgp0RtEgaUQ/Oyb+UTKKlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}