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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '185031cea9cda7971893ed39372b005d54cd8168ae49dc7f26cf8f72d6aa6f6e' 
  AND token = 'cmTUkdGumjJ9WcyuNTU4N5L9UT4EY3p6Srj+yXLkUGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}