SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07e9f838699a8860c382f068bc265ae2125e4d46ed5418d672c2cb4e2f3db3e2' 
  AND token = 'RQv39bNRBEEK3XcUq4+A16GLwdJDXProv4wAfLB3024=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}