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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cee454ad779de5d652799d643f12e6c05a9a2fbbce43a3e19b86a29a5ba2802f' 
  AND token = 'sgMvRBwG+RsfcJg9/S3cZF38E1lgFJUXFo0ZdWOtM/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}