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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db393efd5a0a85ca03cbc4eec565768b36a8ec4759ff5d7a65d648f033ff544f' 
  AND token = 'H631D7a4KhHF7oXPgRLngT3ECocFSpESLptzNbaBe5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}