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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59495f725d30aba1984ec3dcdc1cdcb64c94e9a31acd4dc4f8521c0889323935' 
  AND token = 'uRnT/E5IGf1kJkB/vtBAcxkVWD8M+ItPVV9qCQssgok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}