SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37f16bd5f77e080a123d451382b44ce63acaf73e2a46e3902f99fd3e655acfbc' 
  AND token = 'TGoc06LnZz2bCWKdONE2tL7XTc8+UA/ZzL/Z7V1+VfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}