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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af53dcec4b15a49a998fc678588b5e242c3cada67f36353cb0ae84b4a5853297' 
  AND token = 'Qq8LB+/qunV7omO3G84f2jCgI0CMJAuqiH4t7Fn4qKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}