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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40a109fc231ea700695301479e3e8d10a81287f842c4c2fde5cb5a73ecf7ca6a' 
  AND token = 'silAxlJOMIRD8UIEcBmR0Wv3KLRVPj7bRg+mCyV25xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}