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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '277e62aa65d9a86900442e81130f40c48ad057a500803fe2b3fc4595a2427f59' 
  AND token = 'Bgto0H+De0S/PT2dkldxcItM8yGDd3algGN30NJyMJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}