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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5b8a045f2b29647d244d98ec4ae9537d1cb10082b64e1944e539e5bde8385d7' 
  AND token = 'AP39vmwagoViTvSUAWz96W02dG6JqdDenn99s2zOWvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}