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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cc455ec25380318676d26a2a12fbbe482007cbb9ce2bd8518665179002bda4a' 
  AND token = '9DkrXLg+Vv5DHe2sWoTO11XroiHaJzVnZ+WrCkXdSCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}