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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4465921e442257441b6620cca762563199d26c57f82eef0414a1d92d2427f1b6' 
  AND token = '4SGfOwrSuSPXC0FRcdGlfzEz/5JnDSPgvIxH2w1mcFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}