SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdb4d39f2b0e3d4470b974a9a301f53244a94f55721e9fbbd1abc831f61c06e1' 
  AND token = '2a2Rw/DYFtULc20/s2m56VXmdlcMUsWezonmZ2eLzmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}