SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea37e045b26a65b6d508348d7b2632b95649ee8f9e1267232c5eb567a444db80' 
  AND token = 'RBT4zTqThSYzj15FdS8iDJPDiaLY2iFQK8nLKY+RfYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}