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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca6b0701a38645bec6e4c7887ef5062140a11767eedacb1b272513b59d602473' 
  AND token = 'Xhp+PzkgJq0+h/QdfbYlsc8xMioxsc3sUbRQSG5ZDic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}