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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bc8254da920b1f0630bc77024de0b59b0cadee149c8af6cd4b806e4be2f4a05' 
  AND token = 'OHRn3i2yIyq0c+k5GIQXSIas/Ep2Fon9pDUj5goFUEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}