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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49c08ead6e537592a933994723f96db7157045c5b74909ecd6eea7535531199c' 
  AND token = 'mbSic0RLB9B8psMwdBaMEeZYan/Y9t/4MPS3xuOg67w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}