SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a12861aa3f705562f751bc713878a3110b354e89fd47d7a870a6f540b9f27ba' 
  AND token = '7dfBO/1c0mv4ZfpVhbcEmo/eff6ODQh1fnsQoUKHmIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}