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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1b48462bade010f65c972539cbc82303013a8341d841d362ff592767ca797d9' 
  AND token = '7zeNwyWdyx+Q9YxN8/Pv2MUWvIgyLhSaykgAw7nm9pE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}