SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af56286222cf94cabc2d2a6589d6f2d0690905accc57bb85777dac4aa32c5584' 
  AND token = 'GdlwbRwqR/R+FdpKeWg/oM3CuwAAqirG6woICS8ZISU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}