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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da5a8cfaad421399f8a8a45e772b2d7f944c3dec7dbe8a5647f6002cb0db6a3a' 
  AND token = 'kX+Jdes/81IAjtJbIx4QVUx3Es/KYhEzn9IjLbFc6mU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}