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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25871b2106fc3ac804446f66d83c9a60fe1384aca2c9caed1f0e0ae2d2e1e7e0' 
  AND token = '5fkbcDjWvYhPDtAj/7lyJkzKOdr7Yv1bQUCpIM7qymU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}