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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cffb977d5035574509b14be824068462c05acdcab456758697b3ab4b66c62e4f' 
  AND token = 'gF/+0aI2vrN6sF+t/p9TNGrRlUrybNTCq04siwZ0AKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}