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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d262f2bfd523577b7512741918f60767ddd1fbd5a2233851c3a1a3b3a4e3128' 
  AND token = 'yRz3KzDiHTCMeP1RslCxD39vvvnlg5i8aQZAHJsNZa8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}