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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17449361cc901604d0f2e14202f0fca3b45e1508acd969a014953a95eb99b8b8' 
  AND token = '++z4GttTeX3h42JDOuqeIXME9vGTixSnmTZkl5WYq9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}