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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ce63b2e3ab66aaf69482569560c1e01f0c0bfc9d582708403767f19aa222301' 
  AND token = 'IICNpK4a/SUC7ot19OLE1MR/s0QHbM5sMer9MDjafUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}