SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '168efdafb8acc2b971ed9f213f031d211d3236c8ef2521ccd3965414287eb18c' 
  AND token = 'st5zv6hhf4J0oM4TJbpgCQuZA1cgn5A8Sfxo8qG9xfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}