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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2287ce26e49715706ce9e013c90f3bcce5f961f71dd8bdea3c94e24f049d6c53' 
  AND token = 'rn5quHneD7qAOaPrjP6ZnJSMwJ32+kyW4Qp4QUkFdqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}