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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e706b97d048ff94b2ff7886dc6c0f206aeb5c61752b9f2f5778dacb3b690837' 
  AND token = 'O2xAP4fIVqV91oOCHkAkKAZbRZtpRnvxDYpFynxMGlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}