SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e204c4a161ca89423a21e743db988b57faf0b24d03df219d4d741a4c966ea71' 
  AND token = '+eX6H6xhF2VlNZ0/jIQQRqGRabqD87LKf+ryQ3fScak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}