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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58d9073af55454a4fe43709e411aca4c547f55821f672ef0cfeb9bd68359497d' 
  AND token = 'AdbdnmWMGkU333XL3I1JpZf5trEdastrtQ0eZVT3ABs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}