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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d28b85a7da0ed68d53d2fb1ac4ecdac0f13dd7e265f0cddc5e3354eb958f6dc' 
  AND token = 'EP+EMtKoc7a3g77C3l6xAEHxlzhAbrdzwEO+oLfeXp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}