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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76a00920d95c3b2d9a640b120fdeda18cde488f9fccb26795a54775139e6f644' 
  AND token = 'Kcvf7RmpuCEHx3NSsbXPnHg5BooyU8SnK+k2gfrMXtg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}