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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '510f83bafa8371ce99299685157782c3dd44b9bc533a2c467f5ab8e3feaeac6e' 
  AND token = 'x35I5tSeg/d5etVw2QZPbOEGMlZWVGxwdBxZhOu+b/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}