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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf9615eafb859adf5a4a3a877d7e7e2b026885b595b00c4e40e51b1be314b7a6' 
  AND token = 'SI4AVbEBmAM1xlpK7cV7XpIN1ukSl/CfmwRBCW5YupQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}