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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ee1ee7fc385c262f5b2f04ab886a7691a9df513f488b8f1c777bdb6d91b7199' 
  AND token = 'lBiU1d2fDuetTCiax2idV1es422ofsGQ6dmNW5hYBLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}