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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2126ef271253fc2a6f8867df8485230605d3573369a3c38418f83d6aa7b91969' 
  AND token = 'iwkcED2nW64FhhEUelX3WRXB15yXeugFG5sW17+LUQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}