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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65ac1307e12284518495496997e5f19c52ec391f57b6e397d0a433c4d5f6f9c2' 
  AND token = '8E2Z2iY31U8CsE7WdjKbeAQ1WqbgnNp7RO+OVSEzyO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}