SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9495df4582b91149cb9cdbbf6eb6f36ff398e88cd10a4c36972fca9690d7bee3' 
  AND token = 'Ou7F5jn+AZMptS+gFhbd1SumW2qaUsK2YWFoY4CYby0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}