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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a1d97e0ace76264d958470c0787a17ce8274fcf9d3e8d0d09ad808ace6a3189' 
  AND token = 'ZIjteAl9RrfmXP6e4quzqmA32nBW76cwmBMsxfJTgG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}