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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8f405d30c37a69138814264b69dbcdd4ec075e3a5fb346c3af27bec254923c9' 
  AND token = 'a4xlhkEayP3I87vr9QnWMlBXBHkqGsVk5sIveKtirww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}