SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33e0ce55a5e0e21059af6e18f8f079c3fc78a83683e3f095eebdf76c5587a547' 
  AND token = 'lVQgMjENgp9F7HoJr0CLMGiNoOujzpdP11yA67S3+AI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}