SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80474f52532f3f8164eff9eefa3420aea80b3d417487a988b2b957137a63e3eb' 
  AND token = 'n7+5ER/kRcgyDm6Qp59O/GfrDbobriB6pU4ZRLPcQSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}