SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72efda65bf68e239683149099b421620670f95315815c5b4671694d7254c891c' 
  AND token = 'GYcj33TtaQMGSldQCsONsfFQ1hJzGvLpRwMs2/0xyS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}