SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fafc7d636152de80a4cfe2be62acf21b73c157df8f92f80959f28fadad2b95e' 
  AND token = '8y8+uK34ZeuIq/pqfQdYCXCVX38PhmjEeh/lcyIXF44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}