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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1d433af77edf3117091b6c85fef49a7ef0bfcbbd1f59450f44b006810331c3a' 
  AND token = 'IrynQyGWB1BkaEYIR4o5pINQu22+7Ctm8pCl9od3+UA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}