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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '821cc90048ff5fc843c74bd462505f58cdd2202ec9b7ada33dd392d7d065fd02' 
  AND token = '+2hNCSOVt71hv6OjJEluMl2PGv01uy/p8XkU/sl1lTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}